If you mean you want to replace the A, B, C etc that display in gray at the
top of each column then: NO CAN DO.
If your desire to do so is because you want your column labels to always be
visible at the top of the screen, look in the Help file for info on freezing
panes
Actually there are two parts to this
1) display so that row 1 and column A stay in view (can have additional contiguous rows & columns)
2) Print so that for instance Row 1 and Column are repeated (included) on each printed page