There are lots of ways.
You can build an update query and set their value to false.
You could add a button that runs some code.
You could manually do it.
Your question is very vague and tells us nothing about your structure. Do
you have more than one field in a record that is a checkbox? Do you have
more than one table with checkbox fields.
You will have to post specifics if you expect a specific answer.
FYI - I would never post my real email address on a public newsgroup. Let
the SPAM begin! :-(