Does this happen in other applications, too?
'Cause it doesn't sound like something excel does on its own.
If it does, I'd look for some kind of utility--maybe it came with the printer,
maybe it came with the keyboard, or maybe you got it off the web?????
If it only happens in excel, I'd try this:
Close excel
windows start button|Run
excel /safe
Test it out.
If it doesn't happen then, then I'd start looking for "helpful" addins.
Chip Pearson has some notes on how to diagnose startup errors:
http://www.cpearson.com/excel/StartupErrors.htm
And Jan Karel Pieterse has more notes:
http://www.jkp-ads.com/Articles/StartupProblems.asp