Might think about sending as a PDF. There are free converters, this is one:
http://www.primopdf.com/
Do a web search to find others.
Is this a Publisher 2000 document? Many common picture file formats, such as JPEG or
TIFF, create highly compressed picture files. However, the format that Publisher 2000
uses to store embedded or linked pictures in publications is not compatible with file
compression.
As a result, when you insert a picture into a publication, the file size of the
picture that you inserted into the publication may be much larger than the file size
of the original compressed picture file.
Did you do some deleting when creating your publication?
PUB2000: Publication Retains Large File Size When Pages Are Deleted
http://support.microsoft.com/default.aspx?scid=kb;en-us;218725